Chronic Fumonisin Intake Induces Erythrocyte Osmotic Fragility

Erythrocyte osmotic fragility in hyperthermia-susceptible swine.

Anaesthetic-induced malignant hyperpyrexia in humans appears to result from some intrinsic abnormality of muscle (Satnick, 1969; Harrison et aL, 1970; King, Denborough and Zapf, 1972). Evidence points to this defect being in the sarcoplasmic reticulum (Kalow et al., 1970). A certain strain of Landrace pigs manifests a similar condition and has been used as an animal experimental model for the i...

Studies on retinitis pigmentosa in man. II. Erythrocyte osmotic fragility.

The osmotic fragility of erythrocytes from patients with genetically classified forms of retinitis pigmentosa (RP) has been studied. The mean fragility was increased in autosomal dominantly inherited RP, where the dystrophy was expressed regionally in the retina, with both rods and cones affected. In contrast it was normal in patients with the dominantly inherited disease, which leads to a diff...

Erythrocyte fragility in hyperthyroid patients

  Mild anaemia among patients with hyperthyroidism, reduction in intracranial zinc content of erythrocytes and anti- haemolysis of whole blood of patients with Graves, disease under laboratory Condition are the facts which indicate that although erythrocytes are devoid of receptors for thyroid hormones, they are affected by the excess of these hormones. In order to find out the reasons for suc...

Erythrocyte mechanical fragility test.

Studies of Human HbAA Erythrocyte Osmotic Fragility Index of Non-Malarious Blood in the Presence of Five Anti-malarial Drugs

Background: The capacity of human HbAA erythrocytes of non-malarious blood to withstand osmotic stress in the presence of five antimalarial drugs, Chloroquine phosphate, Quinine, FansidarTM, CoartemTM and HalfanTM was studied in vitro. Materials and Methods: Aqueous solutions of four increasing concentrations of the drugs used in this investigation were in the order: 0.2%, 0.4%, 0.6% and 0.8% (...